Replaced Everything
 

My wife has a 2002 Blazer with 149K miles on it. So far we have had to replace the following:

Engine due to head gasket failure
Radiator due to oil contamination from head gasket failure
Replace radiator again as the oil cooler failed
Replaced transmission
Replaced Fuel Pump
Replaced front wheel hubs twice.
My wife is at the garage today getting the front hubs replaced once again because they have failed within a 12 month period.
I don't think there is anything left to replace on this vehicle. We have replaced everything. This must really be a lemon.
I drive a 2000 Chrysler 300 M with 240K on it and I have only had to replace the transmission due to wear. It is rediculous that we have had to replace all these items out of warranty at such a low mileage.

If it's the stock fuel pump then thats normal that it needs to be replaced. As for the hubs, you might wanna look into what's causing it to fail. I found my problem was the wheel alignment was off a bit. I had some camber on the passenger side wheel which caused the hub to fail twice.

As with anything, if a vehicle is driven hard and/or parts are replaced with cheap replacements, you could see more frequent failures. From the sounds of it, someone treated your blazer pretty poorly.

Also sounds like you have yourself a better than average LH as they had some pretty bad faults as well, most notably the 42LE transmission which you have fallen victim to. By 2000, they had ironed out most of the build quality issues in the 2nd gens and the 300M's were better than their Intrepid & Concorde counterparts for the most part.