My Blazer randomly makes a sound that resembles that of one of those old school crank sirens or something rubbing really hard on the right front tire. Usually happens around 55-60 MPH but only on occasion. When I slow down to about 25MPH it goes away. As I slow down the pitch of the noise gets lower. So I assume that it is something in the tire. In neutral the noise dosen't change when I give it gas. I have checked all brake components and the CV's everything looks fine. Any Clues?????

 

hub bearings??? give them a check..

 

Did that too they look fine.

 

Does the noise go away when you turn?

That's a good indication of it being a hub bearing.

I've replaced three (different ones, on two vehicles) in the past year.

 

It dosen't go away when I turn. This isn't a constant noise. It just happens randomly. The only thing I have found that fixes it is slowing to 20-25MPH.