Hi I’m having a misfire and when I’m in reverse or lower gears my blazer sputters and shakes vigorously when I hit the gas, also when I give it all the gas it has it doesn’t really speed up like it should any help please?? These are the codes below

C0221
C0225
P0135
P0410
P0122
P0300
P0410
P0414

i have tried the following
changed spark plugs
changed spark plug wires
changed throddle posititon sensor