I have a 2000 chevy blazer 4.3L ,2-wheel drive and was wondering how hard is it to replace oil pan gasket...

 

Although I have not done this job, should not be very difficult, unlike what it is on a 4wd.

I doubt that you would even have to raise the front end to do this either.

Will have to rotate the engine in order to get the crankshaft counterweights up so that the pan can clear and come off.

Good luck.