I have a 96 2 door blazer that is 2wd and was trying to rplace the wheels with some newer stock wheels and was wondering if ones from a 4wd blazer would fit, the bolt pattern is the same 5x4.75 but i have been told the offset is different, does that really matter?

 

YES, it does.

4WD wheels on a 2WD truck will be "tucked-in" to the wheel wells.

Inversely, 2WD wheels on a 4WD truck will "stick-out" of the wheel wells.

 

edwsam, I have a 4WD truck and currently have the same wheels you have. They stick out 2" further than stock like bromanjr said (there are pics in my profile 'garage') Putting 4WD wheels on your truck would make them sit in 2". I'm not as familiar with the 2WD variants but there could potentially be issues if the wheels are so far in that they hit the springs or control arms.

However, you could buy a set of 2" wheel spacers which would correct the problem and allow you to run any 4WD wheels. You're lucky because you can add spacers to help fix offset issues, us 4WD folk can't do anything about incorrect offset and just have to deal with the side effects of the wheels sticking out.