Will I be able to clear 33 1250 15s with a 2-in suspension lift? What's a good combination for that size tire?

 

You likely won't be able to fit 33's with only a 2" lift without significant rubbing. Even if you have a ZR2, you'd likely still need to do some aggressive trimming to make it drivable. It also depends significantly on what rims you're using.

Checking out the sticky "What Tires Can I Fit?" and look through the lifting tech section would be a great place to start...

 

You would be able to fit 31's with maybe a bit of of trimming, 32's with a lot of trimming (maybe), but not 33's. This is if you don't have a ZR2. I have a ZR2 with a 2" lift, tweaked tbars and longer shackles in the rear. I ran 33's with some trimming and had no problem on flat ground. Off road with the suspension flexing I would always rub in the rear. Now I just run 32's with no problems at all.